Each method identified 61 percent of values 0.36. At rest, mean values for VD/VT(J) and actual VD/VT were not different: 0.372 0.08 vs 0.376 0.09, p = not significant (NS). Estimates of VD/VT used the Jones' equation (VD/VT) derived from healthy subjects during steady-state exercise or PETC alone (VD/VT) to approximate PaC. To further standardize incremental cardiopulmonary exercise testing, we compared actual VD/VT with estimated VD/VT values in 35 patients referred for evaluation of dyspnea. Determining VD/VT noninvasively uses estimations of arterial PC based on the end-tidal PC. The physiologic dead space/tidal volume ratio (VD/VT) at rest and during exercise is a sensitive measurement of gas exchange that reflects matching of ventilation to perfusion, but requires an invasive measurement for its calculation.
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